By José das Neves, Bruno Sarmento
The all over the world impression of HIV/AIDS is definitely famous. This ebook offers for the 1st time an intensive and demanding assessment of present facets, contemporary advancements, and developments within the formula and drug supply pertaining to anti-HIV microbicides by means of best scientists within the box. also, pertinent regulatory points and socioeconomical concerns on the topic of the topic are mentioned. within the absence of a therapy, prophylaxis represents a cornerstone within the conflict opposed to an infection. One promising approach contains the use round the time of sexual activity of vaginal/rectal items containing antiviral compounds, termed microbicides. it truly is now famous that express improvement of drug dosage kinds and/or drug supply platforms is an fundamental point for the luck of microbicides. diverse teams strived during the last decade to optimize the biophysical and technological functionality of conventional dosage types (gels, pills, and suppositories) to satisfy the specificities of microbicides use, with no neglecting clients’ personal tastes and affordability concerns. furthermore, new formula techniques, reminiscent of vaginal jewelry and movies, nanotechnology-based structures, stimuli-sensitive formulations, designated drug supply structures, between others were proposed and are at present present process pre-clinical or maybe medical checking out.