Basic Immunology: Functions and Disorders of the Immune by Abul K. Abbas MBBS, Andrew H. H. Lichtman MD PhD, Shiv PDF

By Abul K. Abbas MBBS, Andrew H. H. Lichtman MD PhD, Shiv Pillai MBBS PhD

ISBN-10: 032339082X

ISBN-13: 9780323390828

In this up-to-date version of Basic Immunology, the authors proceed to convey a transparent, sleek advent to immunology, making this the most obvious selection for today’s busy scholars. Their event as lecturers, direction administrators, and academics is helping them to distill the center details required to appreciate this complicated box. by using high-quality illustrations, relevant medical instances, and concise, concentrated text, it’s a wonderfully accessible creation to the workings of the human immune approach, with an emphasis on scientific relevance.

  • Concise, clinically centred content is logically organized via mechanism for effective mastery of the material.
  • Features an appendix of scientific cases and CD molecules.
  • Includes numerous full-color illustrations, worthwhile tables, and chapter outlines.
  • Focus questions within every one bankruptcy are perfect for self-assessment and review.
  • Key points bolded through the textual content make it effortless to find very important information.
  • Presents details in a structure and elegance that maximizes usefulness to scholars and teachers learning medication, allied well-being fields, and biology.
  • Fully up-to-date content equips you with the newest proper advances in immunology.
  • Revised and updated artwork complements your visible studying of vital rules and decreases the over the top genuine info present in higher textbooks.
  • Twelve brand-new animations to be had on Student Consult aid additional clarify advanced concepts.
  • Student seek advice book model integrated with buy. This more desirable booklet event gives you entry to the textual content, figures, photographs, word list of immunology phrases, self-assessment questions, and references on numerous units.

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Extra info for Basic Immunology: Functions and Disorders of the Immune System

Example text

In innate immune reactions against infections, enough dendritic cells and macrophages may be activated that large amounts of cytokines are produced, and they may be active distant from their site of secretion (endocrine actions). The cytokines of innate immunity serve various functions in host defense. Tumor necrosis factor (TNF), interleukin-1 (IL-1), and chemokines (chemoattractant cytokines) are the principal cytokines involved in recruiting blood neutrophils and monocytes to sites of infection (described later).

There are five major families of cellular receptors in innate immunity: TLRs, CLRs (C-type lectin receptors), NLRs (NOD-like receptors), RLRs (RIGlike receptors), and CDSs (cytosolic DNA sensors). Formylpeptide receptors (not shown) are involved in ­migration of leukocytes in response to bacteria. Signals generated by engagement of TLRs activate transcription factors that stimulate expression of genes encoding cytokines, enzymes, and other proteins involved in the antimicrobial functions of activated phagocytes and other cells (Fig.

There are five major families of cellular receptors in innate immunity: TLRs, CLRs (C-type lectin receptors), NLRs (NOD-like receptors), RLRs (RIGlike receptors), and CDSs (cytosolic DNA sensors). Formylpeptide receptors (not shown) are involved in ­migration of leukocytes in response to bacteria. Signals generated by engagement of TLRs activate transcription factors that stimulate expression of genes encoding cytokines, enzymes, and other proteins involved in the antimicrobial functions of activated phagocytes and other cells (Fig.

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Basic Immunology: Functions and Disorders of the Immune System by Abul K. Abbas MBBS, Andrew H. H. Lichtman MD PhD, Shiv Pillai MBBS PhD


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