By J. Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle (Eds.)
Each one quantity of Advances in Pharmacology presents a wealthy number of reports on well timed issues. Emphasis is put on the molecular bases of drug motion, either utilized and experimental.
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Thus, in acute inflammation PGE, is undeniably proinflammatory whereas in chronic inflammation a number of anti-inflammatory effects may be in operation. This is particularly relevant to inflammatory diseases such as RA which is characterized by episodes of acute flare up superimposed on a chronic inflammatory state. V. Prostaglandins and Pain The PGs alone do not produce pain, but rather sensitize afferent nociceptors to the effects of other pain producing substances such as BK and histamine (Ferreira, 1972; see Fig.
Drug-Nutr. Interact. 5 , 195. Roe, D. A. (1988). Drug and nutrient interactions in elderly cardiac patients. Drug-Nutr. Interact. 5, 205. Roe, D. A. Drug and food interactions as they affect the nutrition of older individuals. Aging Clin. Exp. Res. 5, 51. Royer, R. , and Bannwarth, B. (1984). Food and drug interactions. World Rev. Nutr. Diet. 43, 117. , Chapin, E. , Brady, E. , and Slater, E. E. Effects of an a2-adrenoceptor antagonist on glucose tolerance in the genetically obese mouse. Metabolism 39,445.
R. Dietary concerns associated with the use of medications. 1. Am. Diet. Assoc. 84, 901. Stiefeld, S. , Graziani, A. , MacGregor, R. , and Esterhai, J. L. (1991). Toxicities of antimicrobial agents used to treat osteomyelitis. Orthop. Clin. North Am. 22, 439. 26 C. Tschanz et al. Thomas, J. , and Tschanz, C. Nutrient-Drug interactions, In “Nutritional Toxicology” (E. N. Kotsonis, M. Mackey, and J. J. ), Target Organ Toxicity Series, p. 139, Raven Press, NY. Thomas, J. , and Thomas, M. J. , Boston.
Advances in Pharmacology, Vol. 35 by J. Thomas August, M.W. Anders, Ferid Murad, Joseph T. Coyle (Eds.)