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By Wang X.-H., Wen Zh.-X.

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8. Turner R, Stratton I, Horton V, et al. UKPDS25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet 1997;350:1288–1293. 9. Eisenbarth GS. Type I diabetes mellitus—a chronic autoimmune disease. N Engl J Med 1986;314:1360–1368. 10. Coutant R, Carel JC, Timsit J, Boitard C, Bougneres P. Insulin and the prevention of insulin-dependent diabetes mellitus. Diabetes Metab 1997;23(Suppl 3):25–28.

The absence of a glycemic threshold for the development of long-term complications: the perspective of the diabetes control and complications trial. Diabetes 1996;45: 1289–1298. 69. UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:857–853. 70. American Diabetes Association. Standards of medical care for patients with diabetes mellitus, position statement.

A trend for a decrease in macrovascular complications was seen, but reached significance only in the subgroup treated with metformin. As discussed previously, intensive treatment of hypertension significantly reduced macrovascular complications, as well as microvascular end points. Thus, it is clear that good glycemic control not only reduces acute complications of diabetes and improves the day-to-day life of the patient, but also prevents the onset and progression of certain chronic complications.

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A Capital Asset Pricing Model Under Stable Paretian Distributions in a Pure Exchange Economy by Wang X.-H., Wen Zh.-X.

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